The physicians adds penicillin to Karen’s drug regimen. Explain the reason for this.

The physicians adds penicillin to Karen’s drug regimen. Explain the reason for this.

Karen, a 48-year-old divorced pilot, and mother of two (ages 10 and 15). Admission assessment includes a history of diabetes. Karen informs you that she has been told by the physician that she has a urinary tract infection with Pseudomonas. The doctor orders aminoglycoside therapy as part of her treatment. She is anxious about her problem and to hurry up and get better.
1. For which two serious toxicities will you monitor, what are their symptoms, and how can they be prevented?
2. The physicians adds penicillin to Karen’s drug regimen. Explain the reason for this.
3. Karen’s “trough” aminoglycoside level is 3.0 mcg/L, and her serum creatinine level is increased from 1.0 to 1.6 within the past two days. Are these results a concern? What should you do? Explain

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