Compare and contrast the actions of g couple proteins and ion gated channels.

Compare and contrast the actions of g couple proteins and ion gated channels.

Compare and contrast the actions of g couple proteins and ion gated channels.

Both the G coupled protein receptors (GCPR) and the ion gated channels allow our cells to communicate with extracellular contents via specific integral receptors embedded into the cell membrane. When ligands bind to the receptor on an ion gated channel, there is a conversion of a chemical signal into an electrical one. As the channel opens it allows K+, Na+, Cl+, and Ca+ to move through the cell membrane and change its electrical properties. Thus, the ion gated channels produce a faster signal than the GCPRs. G-protein coupled receptors compromise the largest family of transmembrane proteins. They convey signals across the membrane in response to the binding of a particular ligand, resulting in the initiation of a cellular signaling cascade and the generation of an intracellular reaction. While the G protein is not the actual receptor, it is a protein that is connected to the receptor and that is activated by a particular ligand that binds to the receptor in order to transmit the activity inside the cell. The activation of an intracellular signaling cascade is induced by GCPRs.

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