Harris (1966) measured the number of genotypes at the alkaline phosphatase locus in the English population. These are three alleles,…
Harris (1966) measured the number of genotypes at the alkaline phosphatase locus in the English population. These are three alleles, designated F, I, and S (for fast, intermediate, and slow mobility in an electrophoretic apparatus). SS SF FF SI FI II 141 111 28 32 15 5 1. what are the observed frequencies of the six genotypes? 2. what are the observed allele frequencies for the three alleles? 3. what are the Hardy-Weinberg equilibrium frequencies of the genotypes? 4. what are the Hardy-Weinberg equilibrium frequencies of the allele? 5. what is the total observed heterozygosity (i.e. the frequency of all heterozygotes)? 6. what is the total heterozygosity at the Hardy-Weinberg equilibrium? 7. Compare the observed and equilibrium heterozygosities. Does this suggest to you any departures from hardy-Weinberg conditions, and if so, what kind of departure?
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