Dopamine D2 receptor occupancy

Dopamine D2 receptor occupancy

QUESTION 3

The PMHNP is discussing dopamine D2 receptor occupancy and its association with aggressive behaviors in patients with the student. Why does the PMHNP prescribe a standard dose of atypical antipsychotics?

A. The doses are based on achieving 100% D2 receptor occupancy.

B. The doses are based on achieving a minimum of 80% D2 receptor occupancy.

C. The doses are based on achieving 60% D2 receptor occupancy.

D. None of the above.

QUESTION 4

Why does the PMHNP avoid prescribing clozapine (Clozaril) as a first-line treatment to the patient with psychosis and aggression?

A. There is too high a risk of serious adverse side effects.

B. It can exaggerate the psychotic symptoms.

C. Clozapine (Clozaril) should not be used as high-dose monotherapy.

D. There is no documentation that clozapine (Clozaril) is effective for patients who are violent.

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